Reduction of Azide to Amine Using Fe/AlC
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Peng-Wu Zheng; Xue-Min Xie; Wei Wang; Xiao-Ji Wang; Yu-Ping Guo; Qi-Dong Tu
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Article
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2006
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John Wiley and Sons
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English
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## Abstract Azides were reduced to the corresponding amines by two new metal/Lewis acid systems in aqueous EtOH with yields ranging from 80% to 95%. The new reduction systems were Fe/AlCl~3~ยท6H~2~O or Fe/BiCl~3~ system in H~2~O/ethanol (2:1, __V__:__V__) at room temperature. Fifteen azides with dif