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Reduction of a 7,12-dimethylbenz[a]anthracene DNA adduct in rat mammary tissue in vivo when pretreated with tamoxifen

✍ Scribed by David Warshawsky; Heather V Dowty; Kathy LaDow; Paul Succop; Glenn Talaska


Book ID
119537311
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
209 KB
Volume
132
Category
Article
ISSN
0378-4274

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Reaction of 7,12-dimethylbenz(a)anthrace
✍ Gerhard Doerjer; Helga Diessner; Joachim Bücheler; Paul Kleihues 📂 Article 📅 1978 🏛 John Wiley and Sons 🌐 French ⚖ 374 KB

## Abstract Pregnant BD‐IX rats (21st day of gestation) received a single IV injection (15 mg/kg) of tritiated 7,12‐dimethylbenz(__a__)anthracene (DMBA), a dose known to induce a high incidence of nervous‐system tumors in the offspring. The animals were killed 12 h later and hydrocarbon‐deoxyribonu