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Determination of Benzo[ a ]pyrene− and 7,12-Dimethylbenz[ a ]anthracene−DNA Adducts Formed in Rat Mammary Glands

✍ Scribed by Todorovic, Rosa; Ariese, Freek; Devanesan, Prabhakar; Jankowiak, Ryszard; Small, Gerald J.; Rogan, Eleanor; Cavalieri, Ercole

Book ID: 121288205
Publisher: American Chemical Society
Year: 1997
Tongue: English
Weight: 235 KB
Volume: 10
Category: Article
ISSN: 0893-228X
DOI: 10.1021/tx970003y

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## Abstract Female Sprague‐Dawley rats were given a subcutaneous injection of the parent hydrocarbon or its K‐region epoxide in 0.1 ml sesame oil on alternate days to a total of 30 doses and observed for sarcoma at the site of injection for 275 days. The parent compounds, benzo(a)__pyrene (0.2 μmol