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Reduction in Fibronectin Expression and Alteration in Cell Morphology Are Coincident in NIH3T3 Cells Expressing a Mutant E2F1 Transcription Factor

โœ Scribed by Kelly L. Jordan-Sciutto; Thomas J. Logan; Pamela A. Norton; Assia Derfoul; George R. Dodge; David J. Hall

Book ID
115602815
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
510 KB
Volume
236
Category
Article
ISSN
0014-4827

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โœ Thomas J. Logan; Kelly L. Jordan; Devon L. Evans; David J. Hall ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 255 KB

The E2F1 transcription factor or an amino terminal deletion mutant termed E2F1d87 was constitutively expressed in NIH3T3 fibroblasts. Cells expressing wild-type E2F1 display a morphology indistinguishable from that of normal fibroblasts. However, the E2F1d87-expressing cells exhibited a distinct rou