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Reduced hippocampal neurogenesis in R6/2 transgenic Huntington's disease mice

✍ Scribed by Joana M.A.C. Gil; Paul Mohapel; Inês M. Araújo; Natalija Popovic; Jia-Yi Li; Patrik Brundin; Åsa Petersén

Book ID
116761800
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
489 KB
Volume
20
Category
Article
ISSN
0969-9961

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## Background Huntington's disease (HD) is a hereditary neurodegenerative disorder caused by a CAG repeat expansion in the __HD__ gene. The huntingtin protein expressed from __HD__ has an unknown function but is suggested to interact with proteins involved in the cell division machinery. The R6/2 t