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Impaired Glutamate Uptake in the R6 Huntington's Disease Transgenic Mice

✍ Scribed by J.-C. Liévens; B. Woodman; A. Mahal; O. Spasic-Boscovic; D. Samuel; L. Kerkerian-Le Goff; G.P. Bates

Book ID
115641653
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
529 KB
Volume
8
Category
Article
ISSN
0969-9961

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## Background Huntington's disease (HD) is a hereditary neurodegenerative disorder caused by a CAG repeat expansion in the __HD__ gene. The huntingtin protein expressed from __HD__ has an unknown function but is suggested to interact with proteins involved in the cell division machinery. The R6/2 t