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Differential Changes in Striatal Projection Neurons in R6/2 Transgenic Mice for Huntington's Disease

✍ Scribed by Z. Sun; N. Del Mar; C. Meade; D. Goldowitz; A. Reiner

Book ID
115641767
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
749 KB
Volume
11
Category
Article
ISSN
0969-9961

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## Background Huntington's disease (HD) is a hereditary neurodegenerative disorder caused by a CAG repeat expansion in the __HD__ gene. The huntingtin protein expressed from __HD__ has an unknown function but is suggested to interact with proteins involved in the cell division machinery. The R6/2 t