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Reduced expression of cellular fos gene in peripheral blood mononuclear cells of patients with primary biliary cirrhosis

✍ Scribed by OGINO, H; INAGAKI, Y; MORIOKA, T; KAWAI, H; UNOURA, M; KAKANUMA, Y; KOBAYASHI, K

Book ID: 123536882
Publisher: Elsevier Science
Year: 1994
Tongue: English
Weight: 731 KB
Volume: 2
Category: Article
ISSN: 0928-4346
DOI: 10.1016/0928-4346(94)90035-3

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Primary biliary cirrhosis (PBC) is a disease that typically affects middle-aged women and is characterized by progressive intrahepatic cholestasis which leads ultimately to cirrhosis, portal hypertension and hepatocellular failure (1). The underlying histopathological lesion in PBC is a chronic, non