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The in vitro production of antibodies to mitochondrial antigens by peripheral blood mononuclear cells from patients with primary biliary cirrhosis

✍ Scribed by Mark I. Avigan; Gregory Adamson; Jay H. Hoofnagle; E. Anthony Jones

Publisher: John Wiley and Sons
Year: 1986
Tongue: English
Weight: 684 KB
Volume: 6
Category: Article
ISSN: 0270-9139
DOI: 10.1002/hep.1840060532

No coin nor oath required. For personal study only.

✦ Synopsis

Primary biliary cirrhosis (PBC) is a disease that typically affects middle-aged women and is characterized by progressive intrahepatic cholestasis which leads ultimately to cirrhosis, portal hypertension and hepatocellular failure (1). The underlying histopathological lesion in PBC is a chronic, nonsuppurative destructive cholangitis. The etiology of PBC is unknown; it is thought to

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