Primary biliary cirrhosis (PBC) is a disease that typically affects middle-aged women and is characterized by progressive intrahepatic cholestasis which leads ultimately to cirrhosis, portal hypertension and hepatocellular failure (1). The underlying histopathological lesion in PBC is a chronic, non
Increased Granulysin Expression in Peripheral Blood Cells of Patients with Primary Biliary Cirrhosis and Its Clinical Implications
โ Scribed by Cheng Qian; Sunxiao Chen; Dingkang Yao; Chuanyong Wu; Tingwang Jiang; Jinshan Ke; Ye Zhou; Mingli Gu; Bo Chen; Anmei Deng; Renqian Zhong
- Publisher
- Springer
- Year
- 2008
- Tongue
- English
- Weight
- 337 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0271-9142
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๐ SIMILAR VOLUMES
The presence of antimitochondrial antibodies (AMA) is a major criterion for the diagnosis of primary biliary cirrhosis (PBC). Although it is not clear that AMA are involved in the pathogenesis of the disease, the study of these autoantibodies has enabled much information to be accumulated about the
To study the expression of MHC Class I1 subregion gene products on biliary epithelial cells in primary biliary cirrhosis, frozen sections from liver biopsies of 15 patients with primary biliary cirrhosis were studied immunohistochemically using HLA-D subregion specific monoclonal antibodies L243 (HL