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Reduced capacitative calcium entry in the mesenteric vascular bed of bile duct-ligated rats

✍ Scribed by Noemí M. Atucha; F. Javier A. Nadal; Antonia Alcaraz; David Iyú; M. Clara Ortiz; Joaquín García-Estañ


Book ID
113585695
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
131 KB
Volume
525
Category
Article
ISSN
0014-2999

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Effects of bile duct ligation on calcium
✍ Nimish Vakil; Anil Sharma; Yoram Yagil 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 662 KB

In an earlier study we showed that bile duct-ligated rats were highly susceptible to gentamicin nephrotoxicity and that oral calcium administration had a pronounced protective effect. The mechanism by which this occurs is unclear. Because cations compete with gentamicin for tubule binding sites, it