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Reduced brain cholesterol content in arylsulfatase A-deficient mice

✍ Scribed by Dieter Lütjohann; Klaus Harzer; Volkmar Gieselmann; Matthias Eckhardt


Book ID
116292718
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
97 KB
Volume
344
Category
Article
ISSN
0006-291X

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## Abstract Many studies have indicated leukocytes are a major contributor to brain injuries caused by intracerebral hemorrhage (ICH). Leukocyte‐expressed CD18 is important for neutrophil–endothelial interactions in the vasculature, and CD18 deficiency protects against ischemia‐reperfusion injury.