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Accumulation of lysosulfatide in the brain of arylsulfatase A-deficient mice

✍ Scribed by Maria Blomqvist; Volkmar Gieselmann; Jan-Eric Månsson

Book ID
115020470
Publisher
BioMed Central
Year
2011
Tongue
English
Weight
198 KB
Volume
10
Category
Article
ISSN
1476-511X

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Deficient glycosylation of arylsulfatase A in pseudo arylsulfatase-A deficiency
✍ M. Ameen; D. A. Lazzarino; B. M. Kelly; C. A. Gabel; P. L. Chang 📂 Article 📅 1990 🏛 Springer 🌐 English ⚖ 886 KB

Deficient arylsulfatase-A activity is diagnostic of a neurodegenerative human lysosomal storage disease, metachromatic leukodystrophy. Paradoxically, similar enzyme deficiency also occurs in normal individuals, who are known as being pseudo arylsulfatase-A deficient. We showed previously that this p