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Red cell pyruvate kinase deficiency: An optimised assay

✍ Scribed by Max Lakomek; Werner Schröter; Heinz Winkler

Book ID: 115823167
Publisher: Elsevier Science
Year: 1980
Tongue: English
Weight: 698 KB
Volume: 108
Category: Article
ISSN: 0009-8981
DOI: 10.1016/0009-8981(80)90289-2

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## Abstract Pyruvate kinase deficient red blood cells have an abnormal tendency to lose ATP when exposed to low pO~2~ or cyanide, whereas normal red cells do not. Once energy is depleted, all red cells take up calcium and subsequently lose intracellular potassium and water. It has been shown previo