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Membrane Abnormalities of Pyruvate Kinase Deficient Red Cells

✍ Scribed by A. Zanella; A. Brovelli; A. Mantovani; C. Izzo; P. Rebulla; C. Balduini

Book ID
114709022
Publisher
John Wiley and Sons
Year
1979
Tongue
English
Weight
504 KB
Volume
42
Category
Article
ISSN
0007-1048

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## Abstract Pyruvate kinase deficient red blood cells have an abnormal tendency to lose ATP when exposed to low pO~2~ or cyanide, whereas normal red cells do not. Once energy is depleted, all red cells take up calcium and subsequently lose intracellular potassium and water. It has been shown previo