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Recurrent Cytogenetic Aberrations and Loss of Constitutional Heterozygosity in Ovarian Carcinomas

✍ Scribed by Marion Kiechle-Schwarz; Thomas Bauknecht; Ullrich Karck; Friedrich Kommoss; Andreas du Bois; Albrecht Pfleiderer


Book ID
115616297
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
484 KB
Volume
55
Category
Article
ISSN
0090-8258

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## Abstract Frequent loss of heterozygosity (LOH) on both arms of chromosome 17 has been described in ovarian carcinoma (OC) by a number of groups, and the recent fine mapping of an inherited breast‐ovarian cancer gene (__brc__Al) to a small region at 17q 12–21 has focused interest on this area. We