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Recombinational DNA repair: the ignored repair systems

✍ Scribed by Kendric C. Smith

Publisher: John Wiley and Sons
Year: 2004
Tongue: English
Weight: 75 KB
Volume: 26
Category: Article
ISSN: 0265-9247
DOI: 10.1002/bies.20109

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✦ Synopsis

Abstract

The recent finding of a role for the recA gene in DNA replication restart does not negate previous data showing the existence of recA‐dependent recombinational DNA repair, which occurs when there are two DNA duplexes present, as in the case for recA‐dependent excision repair, for postreplication repair (i.e., the repair of DNA daughter‐strand gaps), and for the repair of DNA double‐strand breaks. Recombinational DNA repair is critical for the survival of damaged cells. BioEssays 26:1322–1326, 2004. © 2004 Wiley Periodicals, Inc.

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