Recombinant human growth hormone poly(lactic-co-glycolic acid) microsphere formulation development
β Scribed by Jeffrey L Cleland; OluFunmi L Johnson; Scott Putney; Andrew J.S Jones
- Book ID
- 114176457
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 621 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0169-409X
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π SIMILAR VOLUMES
The development of a stable sustained-release formulation of recombinant human nerve growth factor (rhNGF) for the treatment of neuronal diseases is described. The protein was encapsulated into poly(lactic-co-glycolic) acid (PLGA) microspheres using a spray freeze drying technique. Liquid nitrogen a
## Abstract This article describes the effects of six processing parameters on the release kinetics of a model drug Texas red dextran (TRD) from poly(propylene fumarate)/poly(lacticβ__co__βglycolic acid) (PPF/PLGA) blend microspheres as well as the degradation of these microspheres. The microsphere
## Abstract We developed poly(propylene fumarate)/poly(lacticβ__co__βglycolic acid) (PPF/PLGA) blend microspheres and investigated the effects of various processing parameters on the characteristics of these microspheres. The advantage of these blend microspheres is that the carbonβcarbon double bo