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The Stability of Recombinant Human Growth Hormone in Poly(lactic-co-glycolic acid) (PLGA) Microspheres

✍ Scribed by Jeffrey L. Cleland; Anne Mac; Brooks Boyd; Janet Yang; Eileen T. Duenas; Douglas Yeung; Dennis Brooks; Chung Hsu; Herman Chu; Venkat Mukku; Andrew J. S. Jones

Book ID: 110308715
Publisher: Springer US
Year: 1997
Tongue: English
Weight: 624 KB
Volume: 14
Category: Article
ISSN: 0724-8741
DOI: 10.1023/a:1012031012367

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## Abstract Regeneration of peripheral nerves after injury is suboptimal. We now report the long term delivery of nerve growth factor (NGF) by biodegradable poly‐lactic‐__co__‐glycolic acid (PLGA) microspheres __in vitro__ and __in vivo__. Lactic to glycolic acid ratios of 50:50 and 85:15 were fabr