Formulation and release characteristics of poly(lactic-co-glycolic acid) microspheres containing chemically modified protein
β Scribed by Tae-Kyoung Kim; Diane J. Burgess
- Book ID
- 111768611
- Publisher
- Pharmaceutical Press
- Year
- 2001
- Tongue
- English
- Weight
- 163 KB
- Volume
- 53
- Category
- Article
- ISSN
- 2042-7158
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## Abstract This article describes the effects of six processing parameters on the release kinetics of a model drug Texas red dextran (TRD) from poly(propylene fumarate)/poly(lacticβ__co__βglycolic acid) (PPF/PLGA) blend microspheres as well as the degradation of these microspheres. The microsphere
## Abstract Regeneration of peripheral nerves after injury is suboptimal. We now report the long term delivery of nerve growth factor (NGF) by biodegradable polyβlacticβ__co__βglycolic acid (PLGA) microspheres __in vitro__ and __in vivo__. Lactic to glycolic acid ratios of 50:50 and 85:15 were fabr