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In vitro and in vivo evaluation of taxol release from poly(lactic-co-glycolic acid) microspheres containing isopropyl myristate and degradation of the microspheres

✍ Scribed by Ya Min Wang; Hitoshi Sato; Isamu Horikoshi

Book ID
114163317
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
669 KB
Volume
49
Category
Article
ISSN
0168-3659

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## Abstract Regeneration of peripheral nerves after injury is suboptimal. We now report the long term delivery of nerve growth factor (NGF) by biodegradable poly‐lactic‐__co__‐glycolic acid (PLGA) microspheres __in vitro__ and __in vivo__. Lactic to glycolic acid ratios of 50:50 and 85:15 were fabr