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In vitro and in vivo evaluation of clarithromycin/poly(lactic acid) microspheres for intramuscular drug delivery

✍ Scribed by P.K. Gupta; H. Johnson; C. Allexon

Book ID: 113275566
Publisher: Elsevier Science
Year: 1993
Tongue: English
Weight: 914 KB
Volume: 26
Category: Article
ISSN: 0168-3659
DOI: 10.1016/0168-3659(93)90190-g

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## Abstract Regeneration of peripheral nerves after injury is suboptimal. We now report the long term delivery of nerve growth factor (NGF) by biodegradable poly‐lactic‐__co__‐glycolic acid (PLGA) microspheres __in vitro__ and __in vivo__. Lactic to glycolic acid ratios of 50:50 and 85:15 were fabr