Recognition and inhibition of HIV integr
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Michael Taktakishvili; Nouri Neamati; Yves Pommier; Vasu Nair
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Article
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2000
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Elsevier Science
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English
โ 140 KB
The viral enzyme, HIV integrase, is involved in the integration of viral DNA into host cell DNA. In the quest for a small nucleotide system with nuclease stability of the internucleotide phosphate bond and critical structural features for recognition and inhibition of HIV-1 integrase, we have discov