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Receptor mediated glucocorticoid inhibition of protein synthesis in isolated bone cells

✍ Scribed by Jae Choe; Paula Stern; David Feldman


Book ID
116000964
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
881 KB
Volume
9
Category
Article
ISSN
0022-4731

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Glucocorticoid hormone receptor mediated
✍ Michael Karin; Harvey R. Herschman πŸ“‚ Article πŸ“… 1980 πŸ› John Wiley and Sons 🌐 English βš– 474 KB

## Abstract HeLa cells grown in chemically defined medium lacking glucocorticoids synthesize metallothioneins, low molecular‐weight heavy‐metal binding proteins. Dexamethasone and hydrocortisone increase the rate of metal‐lothionein synthesis five‐ to ten‐fold. Maximal induction is achieved with 10