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Recent developments in Foetal Haemoglobin Research

✍ Scribed by Kamuzora, Hezekiah

Publisher: Springer-Verlag
Year: 1975
Weight: 615 KB
Volume: 30
Category: Article
ISSN: 0018-7348
DOI: 10.1007/bf00279185

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✦ Synopsis

There have been numerous new contributions to the knowledge of foetal haemoglobin over the last few years. It is, therefore, timely to review them together. They throw light on the arrangement on the chromosome of non-alpha chain genes, and on the condition generally known as Hereditary Persistence of Foetal Haemoglobin (HPFH) and have contributed to other aspects of human ontogeny and physiology.

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## It has been found that the alkali-denaturation technique for the identijication of foetal haemoglobin is unsatisfactory for bloodstains more than two weeks old. Electrophoresis on Sartorius cellulose acetate provides a se$aration of haemoglobins A and F in one hour using small amounts of bloods