Foetal haemoglobin in sickle cell anaemia
โ Scribed by R.C. Jain
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 129 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0035-9203
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๐ SIMILAR VOLUMES
There have been numerous new contributions to the knowledge of foetal haemoglobin over the last few years. It is, therefore, timely to review them together. They throw light on the arrangement on the chromosome of non-alpha chain genes, and on the condition generally known as Hereditary Persistence
## Acta (1989), The time, 1956, was right for working on the structure of an abnormal human haemoglobin, suspected to be the cause of sickle-cell anaemia. The disease was called a molecular disease by Pauling in 1949, the first time this notion had been applied, implying that an abnormal molecule
## It has been found that the alkali-denaturation technique for the identijication of foetal haemoglobin is unsatisfactory for bloodstains more than two weeks old. Electrophoresis on Sartorius cellulose acetate provides a se$aration of haemoglobins A and F in one hour using small amounts of bloods