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Recent advances in the structure-activity relationships of substituted corticosteroids

✍ Scribed by Michael J. Green; Satish C. Bisarya; Hershel L. Herzog; Richard Rausser; Elliot L. Shapiro; Ho-Jane Shue; Betty Sutton; Robert L. Tiberi; Margaret Monahan; Elliott J. Collins


Book ID
116000275
Publisher
Elsevier Science
Year
1975
Tongue
English
Weight
642 KB
Volume
6
Category
Article
ISSN
0022-4731

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Following up on the observation that the dynorphin analog [Pro(3)]Dyn A(1-11)-NH(2) 2 possesses high affinity and selectivity for the kappa opioid receptor, a number of related peptides were prepared and characterized by radioligand binding and [(35)S]GTPgammaS assays. While incorporation of 2-azeti