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Rearrangement of the BCR/ABL and TCR-β genes in lymph node blast crisis diagnosed of chronic myeloid leukemia

✍ Scribed by A. Villegas; F. A. González


Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
124 KB
Volume
45
Category
Article
ISSN
0361-8609

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Cytogenetic and molecular studies were performed on 20 interferon-␣ receiving Turkish chronic myelocytic leukemia patients. Four different restriction endonucleases and bcr-G probe were used for southern blot analysis to detect rearrangements of the bcr gene. The RT-PCR method was also applied to de