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Real-time detection of insulin-like growth factor-1 stimulation of the MAC-T bovine mammary epithelial cell line

โœ Scribed by Rose Marie Robinson; R. Michael Akers; Kimberly E. Forsten


Book ID
111637593
Publisher
Springer
Year
2000
Tongue
English
Weight
133 KB
Volume
13
Category
Article
ISSN
0969-711X

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Insulin-like growth factor binding prote
โœ Constance J. Grill; Wendie S. Cohick ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 215 KB ๐Ÿ‘ 2 views

IGF-I is mitogenic for the bovine mammary epithelial cell line MAC-T. In addition, IGF-I specifically upregulates IGFBP-3 synthesis in these cells. To investigate this effect on cell growth and IGF-I responsiveness, cell lines were developed that constitutively express IGFBP-3. MAC-T cells transfect