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Real-time RT-PCR quantification of insulin-like growth factor (IGF)-1, IGF-1 receptor, IGF-2, IGF-2 receptor, insulin receptor, growth hormone receptor, IGF-binding proteins 1, 2 and 3 in the bovine species

✍ Scribed by M.W Pfaffl; T.Mircheva Georgieva; I.Penchev Georgiev; E Ontsouka; M Hageleit; J.W Blum


Book ID
117565235
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
176 KB
Volume
22
Category
Article
ISSN
0739-7240

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## Background and Objectives: We have previously shown that insulin-like growth factor (IGF)-responsive murine sarcomas demonstrate inhibition of local and metastatic disease growth when implanted in an IGF-deficient host animal. In this experiment, we tested whether IGF receptor (IGF-R) and ligan