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Reactivity of asymmetric benzo-condensed diazines with nitrilimine dipoles in the 1,3-dipolar cycloaddition reactions

✍ Scribed by Antonino Lauria; Annalisa Guarcello; Gabriella Macaluso; Gaetano Dattolo; Anna Maria Almerico


Publisher
Elsevier Science
Year
2009
Tongue
French
Weight
247 KB
Volume
50
Category
Article
ISSN
0040-4039

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Substituent effects in the 1,3-dipolar c
✍ Pitlik, János ;Csaba Jászberényi, J. ;Komáromi, István 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 346 KB

## Abstract The 2‐methylenecephalosporins 1 undergo stereoselective 1,3‐dipolar cycloaddition reactions with diazoalkanes to give exclusively the spirocyclopropylcephalosporins 3. Substituens at C‐3, C‐4 and C‐7 of the cephalosporin nucleus do not display a significant effect on the reactivity of t