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Reactive oxygen species mediates the apoptosis induced by transforming growth factor β2 in human lens epithelial cells

✍ Scribed by Ke Yao; Jian Tan; Wei-zhong Gu; Pan-Pan Ye; Kai-jun Wang

Book ID
116294249
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
160 KB
Volume
354
Category
Article
ISSN
0006-291X

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## Abstract Transforming growth factor‐β1 (TGFβ1) is a multifunctional cytokine that is over expressed during liver hepatocytes injury and regeneration. SV40‐transformed CWSV‐1 rat hepatocytes that are p53‐defective undergo apoptosis in response to choline deficiency (CD) or TGFβ1, which mediates C