We have previously reported that transforming growth factor-beta (TGF-beta) induces apoptosis in fetal hepatocytes in primary culture. This effect was found to be associated with an increase in intracellular reactive oxygen species (ROS) and a lowering of total cellular reduced glutathione (GSH). In
✦ LIBER ✦
Source of early reactive oxygen species in the apoptosis induced by transforming growth factor-β in fetal rat hepatocytes
✍ Scribed by Blanca Herrera; Miguel M Murillo; Alberto Álvarez-Barrientos; Jesús Beltrán; Margarita Fernández; Isabel Fabregat
- Book ID
- 113629002
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 691 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0891-5849
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Cycloheximide prevents apoptosis, reacti
✍
A Sanchez; A M Alvarez; M Benito; I Fabregat
📂
Article
📅
1997
🏛
John Wiley and Sons
🌐
English
⚖ 778 KB
Mitochondrial and microsomal derived rea
✍
Craig D. Albright; Rudolf I. Salganik; Corneliu N. Craciunescu; Mei-Heng Mar; St
📂
Article
📅
2003
🏛
John Wiley and Sons
🌐
English
⚖ 202 KB
## Abstract Transforming growth factor‐β1 (TGFβ1) is a multifunctional cytokine that is over expressed during liver hepatocytes injury and regeneration. SV40‐transformed CWSV‐1 rat hepatocytes that are p53‐defective undergo apoptosis in response to choline deficiency (CD) or TGFβ1, which mediates C
Cycloheximide prevents apoptosis, reacti
✍
A Sanchez; AM Alvarez; M Benito; I Fabregat
📂
Article
📅
1997
🏛
John Wiley and Sons
🌐
English
⚖ 782 KB
Reactive oxygen species mediates the apo
✍
Ke Yao; Jian Tan; Wei-zhong Gu; Pan-Pan Ye; Kai-jun Wang
📂
Article
📅
2007
🏛
Elsevier Science
🌐
English
⚖ 160 KB
Activation of caspases occurs downstream
✍
Blanca Herrera; Margarita Fernández; Alberto M. Álvarez; César Roncero; Manuel B
📂
Article
📅
2001
🏛
John Wiley and Sons
🌐
English
⚖ 513 KB
Epidermal growth factor, but not hepatoc
✍
Isabel Fabregat; Aránzazu Sanchez; Alberto M. Alvarez; Toshikazu Nakamura; Manue
📂
Article
📅
1996
🏛
Elsevier Science
🌐
English
⚖ 490 KB