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Platelet derived growth factor (PDGF)-induced reactive oxygen species in the lens epithelial cells: the redox signaling

✍ Scribed by Kate Chao-Wei Chen; You Zhou; Kuiyi Xing; Kostantyn Krysan; Marjorie F. Lou

Book ID
116455961
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
367 KB
Volume
78
Category
Article
ISSN
0014-4835

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## Abstract The platelet‐derived growth factor receptor (PDGFR) is a tyrosine kinase, implicated in the development and progression of different tumors, including gliomas. Chemoresistance is a common feature of malignant gliomas. Since receptor tyrosine kinases contribute to chemoresistance in tumo