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Reactivation of immobilized penicillin G acylase: Influence of cosolvents and catalytic modulators

✍ Scribed by Valeria Miranda; Lorena Wilson; Constanza Cárdenas; Andrés Illanes

Book ID
113804755
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
177 KB
Volume
68
Category
Article
ISSN
1381-1177

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The possibility of using the multicompartment immobilized enzyme reactor (MIER) in presence of a charged substrate is here explored. Penicillin G acylase is used to convert penicillin G (a free acid, with a pK of 2.6) into two charged products: phenyl acetic acid (PAA, with a pK of 4.2) and 6-aminop