The possibility of using the multicompartment immobilized enzyme reactor (MIER) in presence of a charged substrate is here explored. Penicillin G acylase is used to convert penicillin G (a free acid, with a pK of 2.6) into two charged products: phenyl acetic acid (PAA, with a pK of 4.2) and 6-aminop
β¦ LIBER β¦
Hydrolysis of penicillin G by combination of immobilized penicillin acylase and electrodialysis
β Scribed by Fumihiro Ishimura; Ken-Ichi Suga
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 449 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0006-3592
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Screening of a representative series of immobilized penicillin G acylase biocatalysts (enzyme, cells) using enzyme Γow microcalorimetry is described. Immobilized penicillin G acylase biocatalysts were either prepared in the laboratory by various techniques or obtained from four commercial manufactur