Although enamines are known to be excellent addends in many Michael type reactions, the reaction of enamines with Schiff bases has hitherto never been found in the literatures. We now would like to report the reaction and its stereochemical consequence. Reaction of 1-morpholino-l-cyclohexene (Ia) o
Reactions of Schiff base anions with electrophiles: Role of the initial stereochemistry
โ Scribed by Abdelrhani El Achqar; Marie-Louise Roumestant; Philippe Viallefont
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- French
- Weight
- 209 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0040-4039
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โฆ Synopsis
It fs shown that the reactfvfty towards electrophftes of dfastereomerfc Sckfff bases of *R and *S vatfne, leucfne, phenylalanfne and norvalfne methyl esters wfth (lS,ZS,SS) or (lR,2R,SR) 2-hydroxy 3-pfnanone, is hfghly dependent on the stereochemistry of the startfng product.
๐ SIMILAR VOLUMES
Stereochemistry of the reactions of methyl-, ethyl-, 2propyl-, and 1 ,I -dimethylethylsulfinyl phenylmethyl carbanions with deuterium oxide and methyl iodide in tetrahydro furan have been studied. The 2-propylsulfinyl phenylmethyl carbanion exerts abnormal behavior in the sense that the alkyl substi