𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Reaction of α-Amidoalkylphenyl Sulfones with Lithiated Nitriles: Syn -Selective Synthesis of β-Amino Nitriles

✍ Scribed by Mecozzi, Tiziana; Petrini, Marino; Profeta, Roberto


Book ID
120597815
Publisher
American Chemical Society
Year
2001
Tongue
English
Weight
58 KB
Volume
66
Category
Article
ISSN
0022-3263

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Reaction of α-amidoalkylphenyl sulfones
✍ Tiziana Mecozzi; Marino Petrini 📂 Article 📅 2000 🏛 Elsevier Science 🌐 French ⚖ 113 KB

The reaction of Reformatsky reagents with α-amidoalkylphenyl sulfones proceeds in dichloromethane at room temperature leading to the synthesis of the corresponding β-amino esters in good yields. The procedure presents syn stereoselectivity and can be also extended to Reformatsky reagents based on γ-