The reactions of α,β-unsaturated nitriles (1, 9, 12) as bielectrophiles with aminoazoles (2, 4, 6) as binucleophiles were investigated. Acrylonitrile (1) reacts almost exclusively in a chemoselective Michael-type addition yielding the substituted azoles 3, 5 and 7, respectively. Cinnamonitriles 9a,b
The Reaction of Amino-Imidazoles, -Pyrazoles and -Triazoles with α,β-Unsaturated Nitriles.
✍ Scribed by Sergey A. Komykhov; Konstantin S. Ostras; Alvard R. Kostanyan; Sergey M. Desenko; Valery D. Orlov; Herbert Meier
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 21 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
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