Reaction of C19-diterpene alkaloids with sodium in liquid ammonia
โ Scribed by A. S. Narzullaev; M. S. Yunusov; A. M. Moiseenkov; S. S. Sabirov
- Publisher
- Springer
- Year
- 1989
- Tongue
- English
- Weight
- 239 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0009-3130
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Previous publications 1 from our laboratory have shown that biogenetic-type, asymmetric syntheses of some isoquinoline-and indole-alkaloids are successfully achieved from L-3-(3,4\_dihydroxyphenyl)alanine (L-DOPA) and L-tryptophan, respectively.
## Abstract The behaviour of some primary, secondary, and tertiary arylcarbinyl chlorides towards solutions of sodium in liquid ammonia has been studied. Particular attention has been devoted to the biaralkyls formed.
The ratc of disappearance of solvated electrons by reaction with fluorobcnzcne in ammonia is acce!erated by smal1 conccntrations of methanol; it also bas a "negative activation energy" depending on the methanol concentration. The kinetic dota suggest an csothermic electron attachment-detachment equi