Reaction of acrolein with cytosine and adenine derivatives
β Scribed by Rama S. Sodum; Robert Shapiro
- Book ID
- 107873792
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 806 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0045-2068
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The chemical modification of the base residues in nucleic acids is of importance for structural and functional investigation of RNA and DNA /I/. A search of new specific chemical reactions for this purpose seems to be essential for the future development of this field. We wish to report our observ
## Abstract Chloroacetaldehyde, which reacts selectively with cytosine and adenine nucleotides to give fluorescent ethenoβbridged derivatives, was synthesized bearing a ^14^C label. The chloroacetaldehyde lβ^14^C, prepared from glycerolβ2β^14^C, was used to form ethenoβbridged adenine and cytosine