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Preparation of chloroacetaldehyde-l-14C and its reaction with adenine and cytosine nucleotides

✍ Scribed by John C. Greenfield; Nelson J. Leonard; Robert F. Nystrom

Book ID
102369928
Publisher
John Wiley and Sons
Year
1976
Tongue
French
Weight
274 KB
Volume
12
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

Chloroacetaldehyde, which reacts selectively with cytosine and adenine nucleotides to give fluorescent etheno‐bridged derivatives, was synthesized bearing a ^14^C label. The chloroacetaldehyde l‐^14^C, prepared from glycerol‐2‐^14^C, was used to form etheno‐bridged adenine and cytosine nucleotides for enzyme studies and was applied to the chemical modification of tRNA.

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Application of Elimination Voltammetry t
Application of Elimination Voltammetry to the Resolution of Adenine and Cytosine Signals in Oligonucleotides II. Hetero-Oligodeoxynucleotides with Different Sequences of Adenine and Cytosine Nucleotides
✍ Libuše Trnková; František Jelen; Irena Postbieglová 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 145 KB

## Abstract Elimination voltammetry with linear scan (EVLS) was applied to the resolution of reduction signals of adenine (A) and cytosine (C) residues in short synthetic hetero‐oligodeoxynucleotides (ODNs) with different sequences of A and C. The EVLS evaluation required linear sweep voltammograms