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Rational Development of Histone Deacetylase Inhibitors as Anticancer Agents: A Review

✍ Scribed by Acharya, Milin R. (author);Sparreboom, Alex (author);Venitz, Jürgen (author);Figg, William D. (author)

Book ID
125481525
Publisher
American Society for Pharmacology and Experimental Therapeutics
Year
2005
Tongue
English
Weight
171 KB
Volume
68
Category
Article
ISSN
0026-895X

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## Abstract Cancer is as much an epigenetic disease as it is a genetic and cytogenetic disease. The discovery that drastic changes in DNA methylation and histone modifications are commonly found in human tumors has inspired various laboratories and pharmaceutical companies to develop and study epig