Rational Design, Synthesis, and Evaluati
β
Richardβ
J. Payne; Fabienne Peyrot; Olivier Kerbarh; Andrewβ
D. Abell; Chris Abell
π
Article
π
2007
π
John Wiley and Sons
π
English
β 641 KB
## Abstract The inβ silico design, synthesis, and biological evaluation of ten potent type II dehydroquinase inhibitors are described. These compounds contain an anhydroquinate core, incorporated as a mimic of the enolate reaction intermediate. This substructure is attached by a variety of linking u