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Rational Design of a Novel Fluorescent Biosensor for β-Lactam Antibiotics from a Class A β-Lactamase

✍ Scribed by Chan, Pak-Ho; Liu, Hong-Bing; Chen, Yu Wai; Chan, Kwok-Chu; Tsang, Chun-Wai; Leung, Yun-Chung; Wong, Kwok-Yin


Book ID
120684255
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
117 KB
Volume
126
Category
Article
ISSN
0002-7863

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The nucleotide sequence has been determined of a 1400 bp fragment from the chromosome of Yersinia enterocolitica containing the gene for beta-lactamase I. An ORF of 882 bp was identified, which could code for a polypeptide of 294 amino acids, closely related to other beta-lactamases of molecular cla