Development of a Novel and Automated Fluorescent Immunoassay for the Analysis of β-Lactam Antibiotics
✍ Scribed by Benito-Peña, Elena; Moreno-Bondi, María C.; Orellana, Guillermo; Maquieira, Ángel; van Amerongen, Aart
- Book ID
- 120434081
- Publisher
- American Chemical Society
- Year
- 2005
- Tongue
- English
- Weight
- 269 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0021-8561
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## Abstract Conformational‐energy calculations were carried out on the new family of β‐lactam antibiotics (viz., thienamycin, PS‐5, 1‐oxa‐ and 1‐thiapenems, and their close analogs); these exhibit broad‐spectrum antibacterial activity and stability towards β‐lactamase‐producing strains. The bicycli
The stereoselective synthesis of two precursors of tricyclic β-ring-forming reaction followed by the reduction of a functionalized aromatic substituent at C-4 of the β-lactam lactam antibiotics (trinems) has been attempted by a novel approach that involves a highly stereoselective azetidinone nucleu