Rational design of a fluorescent hydrogen peroxide probe based on the umbelliferone fluorophore

✍ Scribed by Lupei Du; Minyong Li; Shilong Zheng; Binghe Wang

• Book ID: 104095222
• Publisher: Elsevier Science
• Year: 2008
• Tongue: French
• Weight: 210 KB
• Volume: 49
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/j.tetlet.2008.03.063

✦ Synopsis

In this study, we report a novel water-soluble umbelliferone-based fluorescent probe for hydrogen peroxide. This probe shows very large increases (up to 100-fold) in fluorescent intensity upon reaction with hydrogen peroxide, and good selectivity over other reactive oxygen species (ROS).