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Design of OFF/ON fluorescent thiol probes based on coumarin fluorophore

✍ Scribed by Wei Sun, Jing Li, WenHua Li, LiJuan Su, LuPei Du, MinYong Li

Book ID
118137872
Publisher
SP Science China Press
Year
2012
Tongue
English
Weight
851 KB
Volume
55
Category
Article
ISSN
1674-7291

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In this study, we report a novel water-soluble umbelliferone-based fluorescent probe for hydrogen peroxide. This probe shows very large increases (up to 100-fold) in fluorescent intensity upon reaction with hydrogen peroxide, and good selectivity over other reactive oxygen species (ROS).