๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Rates of Uncatalyzed Peptide Bond Hydrolysis in Neutral Solution and the Transition State Affinities of Proteases

โœ Scribed by Radzicka, Anna; Wolfenden, Richard


Book ID
111694451
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
201 KB
Volume
118
Category
Article
ISSN
0002-7863

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Experimental versus theoretical evidence
โœ M. Niyaz Khan ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 176 KB

## Abstract Recent theoretical studies of the alkaline hydrolysis of the amide bond have indicated that the nucleophilic attack of the hydroxide ion at the carbonyl carbon of the amide group is rate limiting. This is shown to be inconsistent with a large amount of experimental observations where th

Transition state isosteres of the ฮณ-glut
โœ Ivana Cacciatore; Antonio Di Stefano; Grazia Luisi; Francesco Pinnen; Piera Sozi ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 100 KB

## Abstract The fully deprotected glutathione analogue containing the aminomethylene unit as transition state isostere of the ฮณโ€Gluโ€Cys peptide bond was synthesized for the first time and characterized in both the reduced and oxidized forms. Copyright ยฉ 2003 European Peptide Society and John Wiley