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Rate of recombination of chromosomes 21 in parents of children with Down syndrome

✍ Scribed by A. J. H. Hamers; H. Meyer; R. J. E. Jongbloed; R. R. W. J. van der Hulst; J. P. M. Geraedts


Book ID
115090047
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
395 KB
Volume
37
Category
Article
ISSN
0009-9163

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The number of 21 chromosomes of 15 individuals with Down's syndrome and their parents were examined in an attempt to determine the parental origin of the extra number 21 chromosome and the stage of meiosis at which nondisjunction occurred. Chromosomes were stained with quinacrine hydrochloride and p